The Cognito HOPE Study for Alzheimer’s disease is investigating a non-invasive wearable study device with the potential to slow the progression of mild to moderate Alzheimer’s.
While many investigational drug treatments directly target widely known amyloid plaques and tau tangles in the brain, this device targets other contributing factors to Alzheimer’s, such as the abnormal electrical activities in the brain. This approach represents an opportunity to treat Alzheimer’s with a new modality and could bring a much-needed treatment option to many impacted by this devastating disease.
There are no medications involved in this study. The investigational medical device consists of headphones and eyewear and delivers treatment through sensory stimulation in the comfort of patients’ homes.
Alzheimer’s is a type of brain disorder that causes problems with memory, thinking and behavior. It is a gradually progressive condition with no current cure. Alzheimer’s currently affects more than 5 million people in the United States and is under-recognized as the sixth leading cause of death in our country. Although Alzheimer’s is the most common form of dementia in ages 65 and older, younger people are being diagnosed with increased frequency.
If you are eligible and choose to enroll in the HOPE Study, you will:
No drugs or highly invasive procedures are involved in the HOPE study. Additionally, no insurance or out-of-pocket expenses are necessary.
By joining the HOPE Study, you will help advance a new way of treating Alzheimer’s. You or your loved one may have access to a novel investigational treatment which may slow the progression of mild to moderate Alzheimer’s.
You or a loved one may be eligible to join the study if you/they are:
Additional Criteria:
In a 6-month long phase-2 study, treatment delivered through this investigational device has shown to significantly slow the progression of Alzheimer’s through preservation of cognitive and daily function, as well as whole brain volume among treated participants.
Patients across multiple clinical studies have completed over 40,000 treatment sessions to date and tolerated the study device well. No treatment limiting serious adverse events were reported.
Talk to your doctor about whether the HOPE Study is a good fit for you or your loved one.